Earls Court will host the Clothes Show London next June as in a change of location from its 2009 home, ExCeL.
The event is moving venues, taking up residency in the west of the city after debuting in the east this year.
It will feature a 2,500-seat theatre, which will put on dance and fashion shows, as well as huge selection of boutique outlets, representing top designers right down to high street stores.
The Nail and Champagne Bar will also return in 2010 after it was found to be a particular highlight in 2009.
New additions include the Fitness Studio, which will feature aerobic demonstrations showcasing the latest sportswear, and the Photographic Studio, where visitors will have the chance to star on the cover of their favourite magazine.
"Clothes Show London 2010 will up the style stakes even further and promises to be bigger and better than ever," said Gavin Brown, managing director of Haymarket Exhibitions, which organises the event.
ExCeL may have lost the Clothes Show, but it will host the newly-created London Golf and Tennis show next spring.